The Panel recommends using anti-SARS-CoV-2 mAbs for the treatment of mild to moderate COVID-19 and for PEP of SARS-CoV-2 infection in individuals who are at high risk for progression to severe COVID-19, as outlined in the FDA EUAs. While there are currently no shortages of these mAbs, logistical constraints (e.g., limited space, not enough staff who can administer therapy) can make it difficult to administer these agents to all eligible patients. In this statement, the Panel offers suggestions for how to prioritize the use of mAbs for treatment or PEP when there are logistical constraints for administering therapy.